Surgical outcomes in focal epilepsy depend on accurate localization of the epileptogenic network. Standard intracranial-EEG review identifies the seizure-onset zone but characterizes propagation incompletely; downstream nodes that contribute to recurrence may remain below the thresholds of conventional detectors.
Neuronium Neuroscience Institute develops a three-step pipeline for epileptogenic-network analysis: localization of the seizure-onset zone from intracranial recordings, identification of energy-dominant network regions that conventional thresholding may attenuate, and projection of both onto the patient's structural connectivity via tractography for surgical review.
The methods have been evaluated on intracranial-EEG recordings from multiple academic medical centers, drawing on both publicly available datasets and de-identified institutional data. Effect sizes are reproducible across institutions, recording modalities, and patient demographics.
Dr. Atik is a neurosurgeon specializing in stereotactic and functional neurosurgery with a clinical focus on epilepsy. The methods described here were developed independently and span signal processing, structural imaging, and three-dimensional surgical visualization.
Inquiries from epilepsy centers, investigators, and prospective collaborators are welcome.
ceo@neuroniuminstitute.com